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382: 2018/02/19(月)15:22 ID:Fcc2edZf(2/8) AAS
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J Physiol. 2018 Feb 15. doi: 10.1113/JP275709. [Epub ahead of print]
Prior ingestion of exogenous ketone monoester attenuates the glycemic response to an oral glucose tolerance test in healthy young individuals.
Myette-Côté E1, Neudorf H1, Rafiei H1, Clarke K2, Little JP1.
外部ﾘﾝｸ:www.ncbi.nlm.nih.gov
外部ﾘﾝｸ:onlinelibrary.wiley.com
KEY POINTS SUMMARY:
・The recent development of exogenous ketone supplements allows direct testing of the metabolic effects of elevated blood ketones without the confounding influence of widespread changes experienced with ketogenic diets or prolonged fasting.
・Here, we determined the effect of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester on glycemic response and insulin sensitivity index during a 2-hour oral glucose tolerance test (OGTT) in humans.
・Results show that consuming a ketone monoester supplement 30 minutes prior to an OGTT reduced glycemic response and markers of insulin sensitivity without affecting insulin secretion.
・This study provides evidence that ketone supplements could have therapeutic potential for future application as a glucose lowering nutritional supplement.
検査30分前のケトンモノエステルサプリ服用で、インスリン分泌に影響を与えずOGTT30分値とインスリン感受性を改善
ただし糖代謝健常者被験者での試験であることに注意
耐糖能異常者ならびに糖尿病患者様はぬか喜びせず、何事もSMBGで確認しながら試すのが肝要
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